A protective mechanism of probiotic Lactobacillus against hepatic steatosis via reducing host intestinal fatty acid absorption

A protective mechanism of probiotic Lactobacillus against hepatic steatosis via reducing host intestinal fatty acid absorption

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Liver disease: Beneficial bacteria divert dietary fats Intestinal bacteria that consume common fatty acids could help protect their hosts against non-alcoholic fatty liver disease (NAFLD).The accumulation of lipids over the course of NAFLD can produce serious inflammation and ultimately lead to liver failure.The gut microbiome plays a prominent role in metabolic health and South Korean researchers led by Hui-Young Lee of Gachon University, Incheon, and weboost splitter Jae-Hak Park of Seoul National University, Seoul, have identified a bacterial species that could help prevent NAFLD.

They found that Lactobacillus rhamnosus GG can absorb oleic acid, a fatty acid commonly found read more in the human diet.Transplantation of these bacteria into high-fat diet-fed mice resulted in weight loss and reduced fat accumulation in the liver.These findings providing a new mechanistic insight into the impact of certain probiotic species on NAFLD.